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1 article(s) from Paiva, Karen L R

Plasma membrane imaging with a fluorescent benzothiadiazole derivative

Pedro H. P. R. Carvalho,
Jose R. Correa,
Karen L. R. Paiva,
Daniel F. S. Machado,
Jackson D. Scholten and
Brenno A. D. Neto

Beilstein J. Org. Chem. 2019, 15, 2644–2654, doi:10.3762/bjoc.15.257

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Graphical Abstract

Figure 1: The 2,1,3-benzothiadiazole (BTD) core and its derivatives that are successfully applied in bioimagi...

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Scheme 1: Synthesis of the plasma membrane BTD probe (BTD-4APTEG) and its structural features.

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Figure 2: (Left) UV–vis, (center) fluorescence emission and (right) solvatochromic effect (Stokes shift in wa...

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Figure 3: Mean absolute error (MAE) comparing both the experimental and the estimated TD-DFT λ_max positions i...

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Figure 4: (A) CAM-B3LYP/6-311+G(d) optimized geometry of BTD-4APTEG (implicit DMSO). (B) TD-DFT UV–vis spectr...

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Figure 5: Cellular viability determined by MTT analysis after 24 h treatment with the developed dye BTD-4APTE...

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Figure 6: MCF-7 cells incubated with BTD-4APTEG (1 μM) in live (A) and (B) and fixed cells (C) and (D). (A) a...

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Figure 7: Co-staining experiments using the commercially available CellMask (red emission) and BTD-4APTEG (gr...

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Published 06 Nov 2019

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